Anti-FLT1(VEGFR1) Antibody

货号:BM1610
应用:WB, IHC
反应性:Human
克隆性:单克隆抗体
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产品概况

货号BM1610
产品名称Anti-FLT1(VEGFR1) Antibody
基因名FLT1
抗体来源Mouse1
克隆Monoclonal (Clone:FLT-11 )
抗体亚型Mouse IgG1
分子量151KD
免疫原A synthetic peptide
内容200ug/ml antibody with PBS ,0.02% NaN3 , 1mg BSA and 50% glycerol.
纯化方式protein G purified.
浓度200ug/ml
产品形态Liquid
保存条件12 months from date of receipt,-20℃ as supplied.6 months 2 to 142℃ after reconstitution.Avoid repeated freezing and thawing.
背景资料Vascular endothelial growth factor receptor 1(FLT1) is a protein that in humans is encoded by the FLT1 gene. Oncogene FLT belongs to the src gene family. It is mapped to 13q12. The deduced 1,338-amino acid protein has a calculated molecular mass of 150.6 kD. It has a 758-amino acid extracellular domain, followed by a 22-amino acid transmembrane region and a 558-amino acid cytoplasmic region containing a cluster of basic amino acids and a tyrosine kinase domain. sFLT-1 was identified in placenta, adult lung, kidney, liver and uterus. Like other members of this family, it shows tyrosine protein kinase activity that is important for the control of cell proliferation and differentiation.
研究类别1. Shibuya M, Yamaguchi S, Yamane A, Ikeda T, Tojo A, Matsushime H, Sato M (May 1990). "Nucleotide sequence and expression of a novel human receptor-type tyrosine kinase gene (flt) closely related to the fms family". Oncogene 5 (4): 519–24. PMID 2158038.2. Entrez Gene: FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)". 3. He, Y., Smith, S. K., Day, K. A., Clark, D. E., Licence, D. R., Charnock-Jones, D. S.Alternative splicing of vascular endothelial growth factor (VEGF)-R1 (FLT-1) pre-mRNA is important for the regulation of VEGF activity.Molec. Endocr.13: 537-545, 1999.
Uniprot IDFLT1: P17948
推荐配套的二抗和检测试剂Boster recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (EK1001) for Western blot, and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (SV0001-1) for IHC(P) and ICC.
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