Anti-CDK7 Antibody(monoclonal, MO-1.1)

货号:BM1617
应用:WB, IHC-F, ICC
反应性:Human
克隆性:单克隆抗体
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BM1617-100ul 100ul EA ¥1780.00 请登录 请登录
BM1617-150ul 150ul EA ¥2580.00 请登录 请登录
BM1617-50ul 50ul EA ¥1060.00 请登录 请登录

产品概况

货号BM1617
产品名称Anti-CDK7 Antibody(monoclonal, MO-1.1)
基因名CDK7
抗体来源Mouse
克隆Monoclonal (Clone: MO-1.1)
抗体亚型Mouse IgG2b
分子量39KD
免疫原Recombinant human Cdk7 protein.
内容200ug/ml antibody with PBS ,0.02% NaN3 , 1mg BSA and 50% glycerol.
纯化方式Ascites
浓度200ug/ml
产品形态Liquid
保存条件12 months from date of receipt,-20℃ as supplied. 6 months 2 to 8℃ after reconstitution. Avoid repeated freezing and thawing.
背景资料CDK-activating kinases(CAKs) are multisubunit proteins that phosphorylate and thus activate certain cyclin-dependent protein kinases in the regulation of cell cycle progression. Cyclin dependent kinase7(CDK7) gene is mapped to chromosome 2p15-cen. CDK7 functions in both cyclin binding and T-loop phosphorylation and that these 2 steps of CDK1 activation are mutually dependent.
研究类别1. Levedakou, E. N.; He, M.; Baptist, E. W.; Craven, R. J.; Cance, W. G.; Welcsh, P. L.; Simmons, A.; Naylor, S. L.; Leach, R. L.; Lewis, T. B.; Bowcock, A.; Liu, E. T. : Two novel human serine/threonine kinases with homologies to the cell cycle regulating Xenopus MO15, and NIMA kinases: cloning and characterization of their expression pattern. Oncogene 9: 1977-1988, 1994.
Uniprot IDCDK7: P50613
推荐配套的二抗和检测试剂Boster recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (EK1001) for Western blot, and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (SV0001-1) for IHC(P) and ICC.

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[list_product_images]Figure 1. IHC analysis of anti- CDK7 antibody (BM1617).detected in paraffin-embedded section of human Breast cancer tissue. Biotinylated goat anti-mouse IgG was used as secondary antibody. The tissue section was developed using Strepavidin-Biotin-Complex (SABC) (Catalog # SA1022) with DAB as the chromogen.[/list_product_images]
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