Anti-CTSL Antibody

货号:BM1578
应用:WB, IHC-F
反应性:Human, Mouse, Rat
克隆性:单克隆抗体
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BM1578-100ul 100ul EA ¥1780.00 请登录 请登录
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产品概况

货号BM1578
产品名称Anti-CTSL Antibody
基因名CTSL1
抗体来源Mouse
克隆Monoclonal (Clone: 33/2)
抗体亚型Mouse IgG1
分子量38KD
免疫原Procathepsin L isolated from the human lung cancer cell line EPLC 32M1.
内容200ug/ml antibody with PBS ,0.02% NaN3 , 1mg BSA and 50% glycerol.
纯化方式Ascites
浓度200ug/ml
产品形态Liquid
保存条件12 months from date of receipt,-20℃ as supplied. 6 months 2 to 8℃ after reconstitution. Avoid repeated freezing and thawing.
背景资料Cathepsin L is a lysosomal cysteine proteinase with a major role in intracellular protein catabolism. It also shows the most potent collagenolytic and elastinolytic activity in vitro of any of the cathepsins. Cathepsin L has been implicated in pathologic processes including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. Human liver cathepsin L consists of a heavy chain of about 25 kD and a light chain of about 5 kD. The gene is mapped to 9q21-q22. Cathepsin L is required for endothelial progenitor cell-induced neovascularization.
研究类别1. Fan, Y.-S.; Byers, M. G.; Eddy, R. L.; Joseph, L.; Sukhatme, V.; Chan, S.-J.; Shows, T. B. : Cathepsin L (CTSL) is located in the chromosome 9q21-q22 region: a related sequence is located on chromosome 10. (Abstract) Cytogenet. Cell Genet. 51: 996 only, 1989. 2. Urbich, C.; Heeschen, C.; Aicher, A.; Sasaki, K.; Bruhl, T.; Farhadi, M. R.; Vajkoczy, P.; Hofmann, W. K.; Peters, C.; Pennacchio, L. A.; Abolmaali, N. D.; Chavakis, E.; Reinheckel, T.; Zeiher, A. M.; Dimmeler, S. : Cathepsin L is required for endothelial progenitor cell-induced neovascularization. Nature Med. 11: 206-213, 2005.
Uniprot IDCTSL1: P07711
推荐配套的二抗和检测试剂Boster recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (EK1001) for Western blot, and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (SV0001-1) for IHC(P) and ICC.

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[list_product_images]Figure 1. CTSL1(BM1578)(MW:38KD)HepG2细胞裂解,免疫印迹分析. |Figure 2. CTSL1(BM1578)小鼠肾标本,石蜡切片,SABC法,DAB显色. |Figure 3. CTSL1(BM1578)肠癌标本,石蜡切片,SABC法,DAB显色. |Figure 4. CTSL1(BM1578)肺癌标本,石蜡切片,SABC法,DAB显色.[/list_product_images]
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