Anti-CDK6 Antibody(monoclonal, DCS-90)

货号:BM1616
应用:WB, ICC
反应性:Human, Mouse, Rat
克隆性:单克隆抗体
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BM1616-100ul 100ul EA ¥1780.00 请登录 请登录
BM1616-150ul 150ul EA ¥2580.00 请登录 请登录
BM1616-50ul 50ul EA ¥1060.00 请登录 请登录

产品概况

货号BM1616
产品名称Anti-CDK6 Antibody(monoclonal, DCS-90)
基因名CDK6
抗体来源Mouse
克隆Monoclonal (Clone: DCS-90)
抗体亚型Mouse IgG1
分子量37KD
免疫原Recombinant human Cdk6 protein.
内容200ug/ml antibody with PBS ,0.02% NaN3 , 1mg BSA and 50% glycerol.
纯化方式Ascites
浓度200ug/ml
产品形态Liquid
保存条件12 months from date of receipt,-20℃ as supplied. 6 months 2 to 8℃ after reconstitution. Avoid repeated freezing and thawing.
背景资料The cyclin-dependent protein kinases(CDKs) regulate major cell cycle transitions in eukaryotic cells. Cyclin-dependent kinase-6(CDK6) is the earliest inducible member of the CDK family in human T lymphocytes, involved in growth factor stimulation and cell cycle progression. Germline mutations in CDK6 do not make a significant contribution to melanoma predisposition. CDK6 gene is mapped at 7q21-q22.
研究类别1. Chilosi, M.; Doglioni, C.; Yan, Z.; Lestani, M.; Menestrina, F.; Sorio, C.; Benedetti, A.; Vinante, F.; Pizzolo, G.; Inghirami, G. : Differential expression of cyclin-dependent kinase 6 in cortical thymocytes and T-cell lymphoblastic lymphoma/leukemia. Am. J. Path. 152: 209-217, 1998.2. Shennan, M. G.; Badin, A.-C.; Walsh, S.; Summers, A.; From, L.; McKenzie, M.; Goldstein, A. M.; Tucker, M. A.; Hogg, D.; Lassam, N. : Lack of germline CDK6 mutations in familial melanoma. Oncogene 19: 1849-1852, 2000. 3. Lien, H.-C.; Lin, C.-W.; Huang, P.-H.; Chang, M.-L.; Hsu, S.-M. : Expression of cyclin-dependent kinase 6 (cdk6) and frequent loss of CD44 in nasal-nasopharyngeal NK/T-cell lymphomas: comparison with CD56-negative peripheral T-cell lymphomas. Lab. Invest. 80: 893-900, 2000.
Uniprot IDCDK6: Q00534
推荐配套的二抗和检测试剂Boster recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (EK1001) for Western blot, and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (SV0001-1) for IHC(P) and ICC.
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