Anti-Hexokinase 2/HK2 Antibody

货号:A01389
品牌:博士德
应用:WB
反应性:Human
克隆性:多克隆抗体
抗体来源:Rabbit
存储条件:-20℃
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A01389-100ul 100ul EA ¥1780.00 请登录 请登录
A01389-150ul 150ul EA ¥2580.00 请登录 请登录
A01389-50ul 50ul EA ¥1060.00 请登录 请登录
A01389-100μl 100μl ¥1960.00 请登录 请登录
A01389-150μl 150μl ¥2780.00 请登录 请登录
A01389-50μl 50μl ¥1180.00 请登录 请登录

产品概况

货号 A01389
产品名称 Anti-HK2 Antibody
基因名 HK2
抗体来源 Rabbit
克隆 Polyclonal
抗体亚型 Rabbit IgG
分子量 102KD
免疫原 A synthetic peptide corresponding to a sequence in the middle region of human Hexokinase II (460-497aa AYRLADQHRARQKTLEHLQLSHDQLLEVKRRMKVEME R), different from the related mouse and rat sequences by four amino acids.
内容 500 ug/ml antibody with PBS ,0.02% NaN3 , 1 mg BSA and 50% glycerol.
纯化方式 Immunogen affinity purified.
浓度 500 ug/ml
产品形态 Liquid
保存条件 12 months from date of receipt,-20℃ as supplied. 6 months 2 to 8℃ after reconstitution. Avoid repeated freezing and thawing.
背景资料 Hexokinase 2, also known as HK2, is an enzyme which in humans is encoded by the HK2 gene on chromosome 2. Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.
研究类别 1. "Entrez Gene: HK2 hexokinase 2".2. Printz RL, Osawa H, Ardehali H, Koch S, Granner DK (Feb 1997). "Hexokinase II gene: structure, regulation and promoter organization". Biochemical Society Transactions. 25 (1): 107–12.3. Peng Q, Zhou J, Zhou Q, Pan F, Zhong D, Liang H (2009). "Silencing hexokinase II gene sensitizes human colon cancer cells to 5-fluorouracil". Hepato-Gastroenterology. 56 (90): 355–60.
Uniprot ID HK2: P52789
推荐配套的二抗和检测试剂 Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P). *Blocking peptide 可以联系我们购买。

 

产品应用细节

为了提供最优质的抗体,博士德对每一批抗体都用没有转染过的细胞系和体细胞组织检测,以保证博士德出品的抗体有足够的亲和性足以和对应蛋白天然的表达含量起反应。

应用 稀释度*
Western blot: 1:500-2000

*最优稀释度需要用户自己调试,此处数据仅供参考。

 

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